Author

Y. Rong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2 Animal Behavior & Cognition· 1 Bioengineering· 1 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 9 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

D. Ehrbar· 2 shared N. Mantis· 2 shared Y. Li· 2 shared A. D. Gibson· 1 shared A. J. Eisch· 1 shared A. L. Bayer· 1 shared A. M. Stowe· 1 shared A. W. Frei· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersImmunology

D. Ehrbar

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Thyroid Hormone Suppresses Medulloblastoma Progression Through Promoting Terminal Differentiation of Tumor Cells

Z. Yang, Y. Yang, S. A. Valdes-Rives, Q. Liu, Y. Li, J. Tan, Y. Tan, C. A. Koch, Y. Rong, S. R. Houser, S. Wei, K. Cai, S.-y. Cheng, T. Curran, R. Wechsler-Reya

This study shows thyroid hormone promotes differentiation of medulloblastoma cells, reducing tumor growth by reversing EZH2-mediated repression of NeuroD1.

bioRxiv · Feb 13, 2024Cancer Biology

Maize COI1 quadruple-knockout mutants exhibit elevated DELLA protein accumulation, stunted growth, and reduced photosynthetic efficiency

L. Feiz, C. Shyu, S. Wu, K. R. Ahern, I. Gull, Y. Rong, C. J. Artymowicz, M. A. Pineros, Z. Fei, T. P. Brutnell, G. Jander

This study investigates maize COI proteins' roles in growth and defense by analyzing mutants, finding that quadruple mutants show stunted growth, reduced photosynthesis, and DELLA protein accumulation.

bioRxiv · Apr 21, 2023Plant Biology

Air-Liquid-Interface Reorganizes Membrane Lipid and Enhance Recruitment of Slc26a3 to Lipid-Rich Domains in Human Colon

C. M. Tse, Y. Rong, Z. Zhang, R. Lin, R. Sarker, M. Donowitz, V. Singh

The paper shows that air-liquid interface culture increases DRA expression and activity in Caco-2/BBe cells and colonoids by enhancing ceramide-rich platform formation and differentiation.

bioRxiv · Dec 22, 2022 · PreprintCell Biology

An endolysosome membrane transformation process for engulfment of autophagosomes independently of ESCRT

Y. Rong, Z. Wu, Y. Wang, C. Li, F. Liu

The paper identifies a new endolysosome process, LEA, where autophagosomes are engulfed by extending arms (LF) without fusion, and describes the molecular markers of engulfed autophagosomes.

bioRxiv · May 5, 2022 · PreprintCell Biology

TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells

Y. Rong, J. Jiang, Y. Gao, J. Guo, D. Song, W. Liu, Y. Zhao, B. Xiao, Z. Liu

This study shows TMEM120A does not mediate poking- or stretch-induced currents and identifies a specific coenzyme A-binding site through cryo-EM structures.

bioRxiv · Jun 17, 2021Biophysics

Multi-domain touchscreen-based cognitive assessment of C57BL/6J female mice shows whole body exposure to 56Fe particle space radiation in maturity improves discrimination learning yet impairs stimulus-response habit learning

I. Soler, S. Yun, R. P. Raynolds, C. W. Whoolery, F. H. Tran, P. L. Kumar, Y. Rong, M. J. DeSalle, A. D. Gibson, A. M. Stowe, F. C. Kiffer, A. J. Eisch

This study shows that whole-body exposure to 56Fe radiation in mature female C57BL/6J mice improves hippocampal-dependent discrimination learning but impairs striatal-dependent rule-based learning.

bioRxiv · Jun 9, 2021Animal Behavior & Cognition

In Vitro Platform Establishes Antigen-Specific CD8+ T Cell Cytotoxicity to Encapsulated Cells via Indirect Antigen Recognition

Y. Li, A. W. Frei, E. Yang, I. Labrada-Miravet, C. Sun, Y. Rong, M. M. Samojlik, A. L. Bayer, C. L. Stabler

This paper establishes an in vitro platform to study CD8+ T cell cytotoxicity against encapsulated cells via indirect antigen recognition, revealing that hydrogel encapsulation blocks direct T cell activation but allows indirect activation through host APCs.

bioRxiv · Dec 11, 2019Bioengineering

Fine Specificity Epitope Analysis by HX-MS Identifies Contact Points on Ricin Toxin Recognized by Protective Monoclonal Antibodies

G. Van Slyke, S. K. Angalakurthi, R. T. Toth, D. J. Vance, Y. Rong, D. Ehrbar, Y. Shi, C. R. Middaught, D. Volkin, D. Weis, N. Mantis

This study identifies protective monoclonal antibodies against ricin by mapping their epitopes using HX-MS and shows that specific contact points on RTA correlate with in vivo protection.

bioRxiv · Jun 14, 2018Immunology

TRAIL (CD253) Sensitizes Human Airway Epithelial Cells to Toxin-Induced Cell Death

Y. Rong, J. Westfall, D. Ehrbar, T. LaRocca, N. Mantis

This study shows TRAIL sensitizes Calu-3 cells to ricin-induced apoptosis through extrinsic pathways, with significant upregulation of IL-6.

bioRxiv · May 15, 2018Immunology