Author
University of PittsburghORCID 0000-0003-0403-5326Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Rithika Sankar, Bryona M Jackson, Santana M. Lardo…·Sarah Hainer
This study shows that FACT depletion in stem cells causes a sequence of chromatin disruptions leading to transcriptional collapse.
Sarah A. Tripplehorn, Santana M. Lardo, Margaret K. Shirra…·Karen M. Arndt
A. Maloy, Sydney Walter, A. Mascilli…·Divay Chandra
This study identifies FBXO24 as the E3 ligase regulating FoxP1 ubiquitination and stability, revealing bidirectional regulation between the ligase and its substrate.
Bruce Nmezi, Guillermo Rodríguez Bey, Talia DeFrancesco Oranburg…·Quasar Saleem Padiath
The paper identifies a silencer element lost in ADLD patients that specifically targets oligodendrocyte overexpression of LMNB1, linking it to disease pathogenesis.
Coby Viner, Charles A. Ishak, James Johnson…·Michael M. Hoffman
The paper develops methods to model transcription factor binding in modified DNA by expanding the DNA alphabet and adapting existing tools to handle custom alphabets, identifying modification-sensitive motifs and validating them with experimental data.
David C. Klein, Santana M. Lardo, Kurtis N. McCannell, Sarah J. Hainer
This study shows FACT regulates pluripotency in murine embryonic stem cells by controlling nucleosome positioning and gene expression of pluripotency factors.