The structure of the teleost Immunoglobulin M core provides insights on polymeric antibody evolution, assembly, and function
M. Lyu, A. Malyutin, B. Stadtmueller
The paper reports the cryo-EM structure of teleost IgM, revealing a unique assembly mechanism distinct from mammalian IgM and highlighting evolutionary diversity in pIg structure and function.
bioRxiv · Mar 29, 2023Immunology