The effect of paracrine factors released by irradiated peripheral blood mononuclear cells on neutrophil extracellular trap formation
K. Klas, A. S. Ondracek, T. M. Hofbauer, A. Mangold, K. Pfisterer, M. Laggner, D. Copic, M. Direder, D. Bormann, H. J. Ankersmit, M. Mildner
This study shows that secretome from stressed PBMCs inhibits NET formation by reducing ROS, upregulating antioxidant proteins, and inhibiting PAD4 activation.
bioRxiv · May 30, 2022 · PreprintImmunology