Development of Comprehensive Ultraperformance Liquid Chromatography-High Resolution Mass Spectrometry Assays to Quantitate Cisplatin-Induced DNA-DNA Cross-Links
A. S. Groehler, A. Maratova, N. M. Dao, A. Makhmut, O. D. Scharer
The paper develops UPLC-SIM assays to quantify cisplatin-induced intrastrand DNA cross-links and demonstrates their utility in studying cross-link formation and repair kinetics.
bioRxiv · Sep 28, 2022 · PreprintBiochemistry