Author

O. D. Scharer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. D'Souza· 1 shared A. Makhmut· 1 shared A. Maratova· 1 shared A. S. Groehler· 1 shared A. Topolska-Wos· 1 shared C.-L. Tsai· 1 shared E. Jeong· 1 shared H. S. Kim· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. D'Souza

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Author profile →

2 papers

Recent·Most cited

Development of Comprehensive Ultraperformance Liquid Chromatography-High Resolution Mass Spectrometry Assays to Quantitate Cisplatin-Induced DNA-DNA Cross-Links

A. S. Groehler, A. Maratova, N. M. Dao, A. Makhmut, O. D. Scharer

The paper develops UPLC-SIM assays to quantify cisplatin-induced intrastrand DNA cross-links and demonstrates their utility in studying cross-link formation and repair kinetics.

bioRxiv · Sep 28, 2022 · PreprintBiochemistry

Two Interaction Surfaces between XPA and RPA Organize the Preincision Complex in Nucleotide Excision Repair

M. Kim, H. S. Kim, A. D'Souza, K. Gallagher, E. Jeong, A. Topolska-Wos, K. Ogorodnik Le Meur, C.-L. Tsai, M.-S. Tsai, M. Kee, J. A. Tainer, J.-E. Yeo, W. J. Chazin, O. D. Scharer

The paper investigates two interaction surfaces between XPA and RPA in the preincision complex of nucleotide excision repair, showing their distinct roles in complex assembly and NER activity.

bioRxiv · Mar 1, 2022Biochemistry