Author

A. Matchan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

F. Iorio· 2 shared G. Bignell· 2 shared J. Saez-Rodriguez· 2 shared A. Butler· 1 shared B. Fu· 1 shared C. Benes· 1 shared D. Dow· 1 shared E. Anderson· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

F. Iorio

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR/Cas9 screening

M. Garnett, G. Picco, E. Chen, L. Garcia Alonso, F. Behan, E. Goncalves, G. Bignell, A. Matchan, B. Fu, R. Banerjee, E. Anderson, A. Butler, C. Benes, U. McDermott, D. Dow, , J. Saez-Rodriguez

The paper functionally links gene fusions to cancer cell fitness using drug sensitivity and CRISPR-Cas9 data, identifying rare functional fusions and novel therapeutic targets.

bioRxiv · Feb 24, 2019Cancer Biology

Transcription factor activities enhance markers of drug response in cancer

L. Garcia-Alonso, F. Iorio, A. Matchan, N. Fonseca, P. Jaaks, F. Falcone, G. Bignell, S. S. McDade, M. J. Garnett, J. Saez-Rodriguez

The paper uses computational methods to infer transcription factor activities from RNA-seq data and shows their utility as markers for drug response in cancer.

bioRxiv · Apr 21, 2017Cancer Biology