Blocking chondrocyte hypertrophy in conditional Evc knockout mice does not modify osteoarthritis progression
A. Lamuedra, P. Gratal, L. Calatrava, V. L. Ruiz-Perez, A. Palencia-Campos, S. Portal-Nunez, A. Mediero, G. Herrero-Beaumont, R. Largo
This study investigates whether Evc deletion prevents OA progression by inhibiting chondrocyte hypertrophy, finding partial prevention of hypertrophy but no improvement in cartilage damage.
bioRxiv · Oct 29, 2021 · PreprintPathology