A. Meseguer

Renal Cl-/H+ antiporter ClC-5 regulates collagen production and release in Dent Disease models

This study shows that ClC-5 loss-of-function in Dent Disease models increases collagen production and release, contributing to renal fibrosis.

Cross regulation between the molecular clock and kidney inflammatory, metabolic and fibrotic responses

This study investigates the interaction between the molecular clock and kidney fibrosis in experimental models, finding that clock components influence inflammation and fibrosis, while fibrosis alters clock gene expression.

Global gene-expression analysis reveals the molecular processes underlying ClC-5 loss-of-function in novel Dent Disease 1 cellular models

The paper uses human proximal tubule cell models to study gene expression changes caused by ClC-5 loss-of-function mutations, revealing distinct molecular pathways affected by different mutations.