Global gene-expression analysis reveals the molecular processes underlying ClC-5 loss-of-function in novel Dent Disease 1 cellular models
M. Duran, C. Burballa, G. Cantero-Recasens, C. Butnaru, V. Malhotra, G. Ariceta, E. Sarro, A. Meseguer
The paper uses human proximal tubule cell models to study gene expression changes caused by ClC-5 loss-of-function mutations, revealing distinct molecular pathways affected by different mutations.
bioRxiv · Dec 16, 2020 · PreprintPathology