NOX4 regulates TGFβ-induced proliferation and self-renewal in glioblastoma stem cells.
P. Garcia-Gomez, M. S. Dadras, C. Bellomo, A. Mezheyeuski, K. Tzavlaki, A. Moren, L. Caja Puigsubira
This study identifies NOX4 as a key mediator of TGFβ-induced proliferation and self-renewal in glioblastoma stem cells through ROS production and NRF2 regulation.
bioRxiv · Oct 15, 2019Cancer Biology