Author

A. Mezheyeuski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

P. Micke· 2 shared A. De Reynies· 1 shared A. Martin-Bernabe· 1 shared A. Miranda· 1 shared A. Moren· 1 shared A. Portyanko· 1 shared A. W. Zhang· 1 shared B. Glimelius· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

P. Micke

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3 papers

Recent·Most cited

The ratio of cytotoxic lymphocytes to M2-like macrophages is prognostic in immunogenic tumors

A. Mezheyeuski, M. Backman, J. Mattsson, A. Martin-Bernabe, C. Larsson, I. Hrynchyk, K. Hammarström, S. Ström, J. Ekström, S. Mauchanski, S. Khelashvili, M. Agnarsdottir, P.-H. Edqvist, J. Huvila, U. Segersten, , T. Sjöblom

The paper identifies a prognostic signature based on the ratio of cytotoxic lymphocytes to M2-like macrophages in tumor microenvironments, showing better survival prediction than existing immune scores in colon cancer and other high-mutation burden cancers.

bioRxiv · Mar 24, 2021 · PreprintCancer Biology

NOX4 regulates TGFβ-induced proliferation and self-renewal in glioblastoma stem cells.

P. Garcia-Gomez, M. S. Dadras, C. Bellomo, A. Mezheyeuski, K. Tzavlaki, A. Moren, L. Caja Puigsubira

This study identifies NOX4 as a key mediator of TGFβ-induced proliferation and self-renewal in glioblastoma stem cells through ROS production and NRF2 regulation.

bioRxiv · Oct 15, 2019Cancer Biology

Cancer stemness, intratumoral heterogeneity, and immune response across cancers

A. Miranda, P. T. Hamilton, A. W. Zhang, E. Becht, A. Mezheyeuski, J. Bruun, P. Micke, A. De Reynies, B. H. Nelson

The paper assesses the relationship between cancer stemness and immune response across 21 solid cancers, finding negative associations between stemness and anticancer immunity.

bioRxiv · Jun 20, 2018Cancer Biology