Acute perturbation of retromer and ESCPE-1 leads to functionally distinct and temporally resolved defects in endosomal cargo sorting.
A. J. Evans, J. L. Daly, A. N. Anuar, B. Simonetti, P. J. Cullen
This study uses acute perturbation to investigate retromer and ESCPE-1 roles in endosomal cargo sorting, revealing distinct temporal defects in GLUT1 and CI-MPR sorting.
bioRxiv · Nov 12, 2019Cell Biology