Free ISG15 as a dimer generates IL-1β-producing CD8α+ dendritic cells at the site of infection
A. Napolitano, A. G. van der Veen, M. Bunyan, A. Borg, S. Kjaer, A. Beling, K.-P. Knobeloch, E. Frickel
The paper shows free ISG15 dimers enhance IL-1β production by CD8+ dendritic cells during Toxoplasma infection, linking ISG15 to cytokine responses.
bioRxiv · Feb 27, 2017Immunology