Author

A. Osme

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Organism:mouse· 2 Approach:experimental assay· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

F. Cominelli· 2 shared P. Menghini· 2 shared A. Dev· 1 shared A. Gomez-Nguyen· 1 shared A. I. Caplan· 1 shared B. D. Johnson· 1 shared C. Soto· 1 shared G. Bamias· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

F. Cominelli

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

TL1A/DR3 signaling regulates the generation of pathogenic Th9 cells in experimental inflammatory bowel disease

P. Menghini, L. Butto, A. Gomez-Nguyen, N. Aladyshkina, K.-A. Buela, A. Osme, R. Chan, G. Bamias, T. T. Pizarro, F. Cominelli

This study shows that DR3 signaling promotes Th9 cell pathogenicity in CD-like ileitis by enhancing pro-inflammatory signatures and reducing anti-inflammatory responses.

bioRxiv · Feb 9, 2024 · PreprintImmunology

Mesenchymal stem cells ameliorate inflammation in an experimental model of Crohn's disease via the mesentery

M. Dave, A. Dev, R. A. Somoza, N. Zhao, S. Viswanath, P. R. Mina, P. Chirra, V. C. Obmann, G. H. Mahabeleshwar, P. Menghini, B. D. Johnson, J. A. Nolta, C. Soto, A. Osme, L. T. Khuat, , F. Cominelli

This study shows that mesenchymal stem cells (MSCs) reduce inflammation in a mouse model of Crohn's disease by modulating T cells and macrophages in the mesentery, with long-term effects through macrophage reprogramming.

bioRxiv · May 22, 2023 · PreprintImmunology