Author

S. Viswanath

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:Bayesian inference· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:cryo-EM· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:electronic health records· 1

Frequent Co-Authors

A. Dev· 1 shared A. F. Brilot· 1 shared A. I. Caplan· 1 shared A. Lyon· 1 shared A. Maxwell· 1 shared A. Osme· 1 shared A. Sali· 1 shared A. Zelter· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. Dev

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Author profile →

4 papers

Recent·Most cited

The molecular architecture of the desmosomal outer dense plaque by integrative structural modeling

S. Pasani, K. S. Menon, S. Viswanath

This paper uses integrative structural modeling to determine the molecular architecture of the desmosomal outer dense plaque and identifies structural features related to mechanical stress resilience and disease.

bioRxiv · Jun 13, 2023Biophysics

Mesenchymal stem cells ameliorate inflammation in an experimental model of Crohn's disease via the mesentery

M. Dave, A. Dev, R. A. Somoza, N. Zhao, S. Viswanath, P. R. Mina, P. Chirra, V. C. Obmann, G. H. Mahabeleshwar, P. Menghini, B. D. Johnson, J. A. Nolta, C. Soto, A. Osme, L. T. Khuat, , F. Cominelli

This study shows that mesenchymal stem cells (MSCs) reduce inflammation in a mouse model of Crohn's disease by modulating T cells and macrophages in the mesentery, with long-term effects through macrophage reprogramming.

bioRxiv · May 22, 2023 · PreprintImmunology

Molecular architecture of nucleosome remodeling and deacetylase sub-complexes by integrative structure determination

S. Arvindekar, M. J. Jackman, J. K. Low, M. J. Landsberg, J. P. Mackay, S. Viswanath

This study determines the molecular architecture of three NuRD sub-complexes using integrative structural methods, revealing new subunit interfaces and MBD3 localization.

bioRxiv · Nov 25, 2021Biophysics

CM1-driven assembly and activation of Yeast γ-Tubulin Small Complex underlies microtubule nucleation

A. F. Brilot, A. Lyon, A. Zelter, S. Viswanath, A. Maxwell, M. J. MacCoss, E. G. Muller, A. Sali, T. N. Davis, D. A. Agard

This study elucidates the role of the CM1 motif in Spc110p in facilitating γ-Tubulin Small Complex (γTuSC) assembly and γ-Tubulin Ring Complex (γTuRC) formation in yeast.

bioRxiv · Nov 21, 2020Biochemistry