Recapitulating bone development for tissue regeneration through engineered mesenchymal condensations and mechanical cues
A. M. McDermott, S. Herberg, D. E. Mason, H. B. Pearson, J. H. Dawahare, J. M. Collins, R. Tang, A. Patwa, M. W. Grinstaff, D. J. Kelly, E. Alsberg, J. D. Boerckel
This study shows that mechanical loading enhances bone regeneration through engineered mesenchymal condensations, mimicking endochondral ossification without heterotopic bone formation.
bioRxiv · Aug 15, 2018Bioengineering