Spatacsin regulates directionality of lysosome trafficking
A. Pierga, R. Matusiak, M. Cauhape, J. Branchu, M. Boutry, F. Darios
This study identifies spatacsin as a regulator of lysosome directionality by controlling the degradation of AP5Z1, which influences motor protein interactions on lysosomes.
bioRxiv · Jun 17, 2022 · PreprintCell Biology