Author

A. Prasanna

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:mechanistic / dynamical model· 1 Assay:multiome· 1

Frequent Co-Authors

A. K. Vasan· 1 shared E. J. Geddes· 1 shared E. Tajkhorshid· 1 shared N. Haloi· 1 shared P. J. Hergenrother· 1 shared P.-C. Wen· 1 shared W. W. Metcalf· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. K. Vasan

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1 paper

Recent·Most cited

Rationalizing generation of broad spectrum antibiotics with the addition of a primary amine

N. Haloi, A. K. Vasan, E. J. Geddes, A. Prasanna, P.-C. Wen, W. W. Metcalf, P. J. Hergenrother, E. Tajkhorshid

This study uses molecular dynamics simulations and experimental validation to show that adding a primary amine to antibiotics enhances their permeation through the outer membrane of Gram-negative bacteria by aligning dipole moments and forming electrostatic interactions.

bioRxiv · Aug 10, 2021Biophysics