SILAC phosphoproteomics reveals unique signaling circuits in CAR-T cells and the inhibition of B cell-activating phosphorylation in target cells
A. A. Griffith, K. P. Callahan, N. G. King, Q. Xiao, X. Su, A. R. Salomon
The paper uses SILAC phosphoproteomics to compare signaling changes in CAR-T cells and target B cells, finding unique phosphorylation patterns in CAR-T cells and reduced B cell receptor signaling in target cells.
bioRxiv · Sep 10, 2021Cell Biology