BioengineeringbioRxiv
Dormancy-inducing 3D-engineered matrix uncovers mechanosensitive and drug protective FHL2-p21 signaling axis
S. Bakhshandeh, U. Heras, H. M. Taieb…·A. Cipitria
The paper identifies a mechanosensitive FHL2-p21 signaling axis in dormant cancer cells using 3D-engineered matrices, showing its role in drug resistance and potential as a target for therapy.