Author

A. Cipitria

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 5 Biophysics· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 6 Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 4 Organism:human· 4 Assay:imaging· 4 Organism:mouse· 4 Approach:microscopy & imaging analysis· 2 Assay:proteomics· 2

Frequent Co-Authors

D. S. Garske· 4 shared G. N. Duda· 4 shared C. A. Garrido· 3 shared K. Schmidt-Bleek· 3 shared R. Dimova· 2 shared S. A. E. Young· 2 shared S. Amini· 2 shared U. Heras· 2 shared

Activity by Year

2023-2024 · peak 6/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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4 shared papersBioengineering

D. S. Garske

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Extracellular vesicle mobility in collagen I hydrogels is influenced by RGD-binding integrins

N. W. Tam, A. Becker, A. Mangiarotti, A. Cipitria, R. Dimova

This study investigates how extracellular vesicle mobility in collagen I hydrogels is influenced by RGD-binding integrins, showing that integrin inhibition increases EV mobility.

bioRxiv · May 29, 2024 · PreprintBiophysics

Anisotropic Hydrogel Degradation Enhances 3D Collective Mesenchymal Stromal Cell Alignment, Mechanotransduction and Osteogenic Differentiation

C. A. Garrido, D. S. Garske, C. H. Bucher, S. Amini, G. N. Duda, K. Schmidt-Bleek, A. Cipitria

This paper shows that anisotropic hydrogel degradation patterns enhance hMSC alignment, mechanotransduction, and osteogenic differentiation compared to uniform materials.

bioRxiv · Apr 11, 2024Bioengineering

Aging impairs skeletal muscle regeneration by promoting fibro/fatty degeneration and inhibiting inflammation resolution via fibro-adipogenic progenitors

F. Garcia-Carrizo, S. Gohlke, G. Lenihan-Geels, A.-M. Jank, M. Leer, G. A. Soultoukis, M. Oveisi, C. Herpich, C. A. Garrido, G. Kotsaris, S. Poehle-Kronawitter, A. Tsamo-Tetou, A. Graja, M. Ost, L. Villacorta, , T. J. Schulz

This study shows aging impairs muscle regeneration by promoting fibro/fatty degeneration and inhibiting inflammation resolution through reduced Periostin in fibro/adipogenic progenitors.

bioRxiv · Nov 27, 2023 · PreprintPhysiology

3D osteocyte lacunar morphometry of human bone biopsies with high resolution microCT: from monoclonal gammopathy to newly diagnosed multiple myeloma

I. Moreno-Jimenez, S. Heinig, U. Heras, D. S. Maichl, S. Strifler, E. Leich, S. Blouin, P. Fratzl, N. Fratzl-Zelman, F. Jundt, A. Cipitria

This study evaluates 3D osteocyte lacunar morphometry in human bone biopsies from monoclonal gammopathy, smoldering multiple myeloma, and newly diagnosed multiple myeloma using high-resolution microCT, finding changes in density, volume, and shape associated with disease progression.

bioRxiv · Jul 12, 2023Bioengineering

Nonspecific membrane-matrix interactions influence diffusivity of lipid vesicles in hydrogels

N. Tam, O. Schullian, A. Cipitria, R. Dimova

This study investigates how membrane-matrix interactions affect lipid vesicle diffusivity in hydrogels, showing that charge and deformability influence diffusion, and PEGylation enhances it beyond electrostatic effects.

bioRxiv · Feb 3, 2023Biophysics

Dormancy-inducing 3D-engineered matrix uncovers mechanosensitive and drug protective FHL2-p21 signaling axis

S. Bakhshandeh, U. Heras, H. M. Taieb, A. R. Varadarajan, S. M. Lissek, S. M. Huecker, X. Lu, D. S. Garske, S. A. E. Young, A. Abaurrea, M. M. Caffarel, A. Riestra, P. Bragado, J. Contzen, M. Gossen, , A. Cipitria

The paper identifies a mechanosensitive FHL2-p21 signaling axis in dormant cancer cells using 3D-engineered matrices, showing its role in drug resistance and potential as a target for therapy.

bioRxiv · Jan 25, 2023Bioengineering

Hydrogels with stiffness-degradation spatial patterns control anisotropic 3D cell response

C. A. Garrido, D. S. Garske, M. Thiele, S. Amini, S. Real, G. N. Duda, K. Schmidt-Bleek, A. Cipitria

This study develops hydrogels with spatial stiffness-degradation patterns to control anisotropic 3D cell response, showing changes in cell morphology and proliferation over time.

bioRxiv · Jan 25, 2023Bioengineering

From breast cancer cell homing to the onset of early bone metastasis: dynamic bone (re)modeling as a driver of metastasis

S. A. E. Young, A.-D. Heller, D. S. Garske, M. Rummler, V. Qian, A. Ellinghaus, G. N. Duda, B. Willie, A. Grueneboom, A. Cipitria

This study develops a mouse model and multimodal 3D imaging to analyze cancer cell homing and dynamic bone remodeling during early bone metastasis, revealing osteolytic lesions in specific bone regions.

bioRxiv · Jan 24, 2023 · PreprintBioengineering