MHC class Ia molecules facilitate MCK2-dependent MCMV infection of macrophages and virus dissemination to the salivary gland
B. Bosnjak, E. Henze, Y. Lueder, K. T. H. Do, A. Rezalofti, C. Ritter, A. Schimrock, S. Willenzon, H. Georgiev, L. Fritz, M. Galla, K. Wagner, M. Messerle, R. Foerster
This study identifies the MHC-Ia/B2m complex as a receptor for MCK2-mediated MCMV infection of macrophages and shows its role in viral dissemination to salivary glands.
bioRxiv · Oct 5, 2022Immunology