Author

E. Henze

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

T. Kawate· 2 shared A. Rezalofti· 1 shared A. Schimrock· 1 shared B. Bosnjak· 1 shared B. W. Fox· 1 shared C. Ritter· 1 shared E. Gelsleichter· 1 shared F. C. Schroeder· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

T. Kawate

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The C-terminal activating domain promotes Panx1 channel opening

E. Henze, J. Ehrlich, J. L. Robertson, T. Kawate

This paper identifies the C-terminal activating domain (CAD) as essential for Panx1 channel opening, showing how its cleavage repositions the N-terminus to reduce anion accumulation and promote ion permeability.

bioRxiv · Jun 13, 2024 · PreprintBiophysics

ATP-release pannexin channels are gated by lysophospholipids

E. Henze, R. N. Burkhardt, B. W. Fox, T. J. Schwertfeger, E. Gelsleichter, K. Michalski, L. Kramer, M. Lenfest, J. M. Boesch, H. Lin, F. C. Schroeder, T. Kawate

The paper identifies lysophospholipids as activators of pannexin channels, showing they trigger ATP and other metabolite release, and activate inflammasomes in human monocytes.

bioRxiv · Oct 23, 2023Biophysics

MHC class Ia molecules facilitate MCK2-dependent MCMV infection of macrophages and virus dissemination to the salivary gland

B. Bosnjak, E. Henze, Y. Lueder, K. T. H. Do, A. Rezalofti, C. Ritter, A. Schimrock, S. Willenzon, H. Georgiev, L. Fritz, M. Galla, K. Wagner, M. Messerle, R. Foerster

This study identifies the MHC-Ia/B2m complex as a receptor for MCK2-mediated MCMV infection of macrophages and shows its role in viral dissemination to salivary glands.

bioRxiv · Oct 5, 2022Immunology