CASCADES, a novel SOX2 super-enhancer associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma multiforme
U. Shahzad, C. Li, M. Johnston, J. J. Wang, N. Sabha, F. S. Varn, A. Riemenschneider, S. Krumholtz, P. Meda, C. Smith, J. Karamchandani, J. K. Watts, R. G. W. Verhaak, M. Gallo, J. T. Rutka, S. Das
This study identifies CASCADES, a lncRNA that regulates stemness in glioblastoma cancer stem cells by epigenetically controlling SOX2 expression.
bioRxiv · Sep 5, 2020 · PreprintCancer Biology