Protection of rhesus macaques against vaginal SHIV challenges by VRC01 and an anti-α4β7 antibody
G. Calenda, I. Frank, G. Arrode-Bruses, A. Pegu, K. Wang, J. Arthos, C. Cicala, B. Grasperge, J. L. Blanchard, S. Maldonado, K. Roberts, A. Gettie, A. S. Fauci, J. R. Mascola, E. Martinelli
This study shows that combining VRC01 and Rh-4β7 antibodies delays SHIV infection, preserves CD4+ T cells, and alters immune responses in macaques.
bioRxiv · Dec 11, 2018 · PreprintImmunology