Endothelial mTOR maintains hematopoiesis during aging
P. Ramalingam, M. G. Poulos, M. C. Gutkin, L. Katsnelson, A. S. Freire, E. Lazzari, J. M. Butler
This study shows that mTOR signaling in bone marrow endothelial cells is critical for maintaining hematopoiesis during aging, and its inhibition accelerates aging-related hematopoietic decline.
bioRxiv · Mar 13, 2020Cell Biology