Author

A. S. Hinrichs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Evolutionary Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:deep learning· 3 Approach:statistical model· 3 Organism:virus· 3 Assay:whole-genome sequencing· 3 Research Focus:phylogenetics / evolution· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1

Frequent Co-Authors

R. Corbett-Detig· 4 shared Y. Turakhia· 4 shared C. Ye· 3 shared J. McBroome· 3 shared B. Thornlow· 2 shared C. Ruis· 2 shared R. Lanfear· 2 shared A. de Bernardi Schneider· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersEvolutionary Biology

R. Corbett-Detig

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Automated Agnostic Designation of Pathogen Lineages

J. McBroome, A. de Bernardi Schneider, C. Roemer, M. T. Wolfinger, A. S. Hinrichs, A. N. O'Toole, C. Ruis, Y. Turakhia, A. Rambaut, R. Corbett-Detig

The paper introduces an automated method for pathogen lineage designation using phylogenetic trees, offering a consistent alternative to manual curation.

bioRxiv · Feb 3, 2023 · PreprintEvolutionary Biology

Mutational spectra distinguish SARS-CoV-2 replication niches

C. Ruis, T. P. Peacock, L. M. Polo, D. Masone, M. Soledad Alvarez, A. S. Hinrichs, Y. Turakhia, C. Ye, J. McBroome, R. Corbett-Detig, J. Parkhill, R. A. Floto

The paper analyzes SARS-CoV-2 mutational spectra to infer replication niches, finding reduced G>T mutations in Omicron linked to upper respiratory tract replication.

bioRxiv · Sep 27, 2022 · PreprintMicrobiology

matOptimize: A parallel tree optimization method enables online phylogenetics for SARS-CoV-2

C. Ye, B. Thornlow, A. S. Hinrichs, D. Torvi, R. Lanfear, R. Corbett-Detig, Y. Turakhia

matOptimize improves runtime and memory efficiency for SARS-CoV-2 phylogenetic tree optimization, enabling daily maintenance of large-scale phylogenies during the pandemic.

bioRxiv · Jan 12, 2022Evolutionary Biology

Pandemic-Scale Phylogenomics Reveals Elevated Recombination Rates in the SARS-CoV-2 Spike Region

Y. Turakhia, B. Thornlow, A. S. Hinrichs, J. Mcbroome, N. Ayala, C. Ye, N. De Maio, D. Haussler, R. Lanfear, R. Corbett-Detig

The paper develops a novel phylogenomic method to detect recombination events in SARS-CoV-2 genomes, identifying 606 recombination events across 1.6M samples with 2.7% of genomes showing recombinant ancestry, primarily in the Spike protein region.

bioRxiv · Aug 4, 2021 · PreprintEvolutionary Biology