A rapidly evolving polybasic motif modulates bacterial detection by guanylate binding proteins
K. M. Kohler, M. Kutsch, A. S. Piro, G. Wallace, J. Coers, M. F. Barber
The paper shows that a rapidly evolving polybasic motif in primate GBP proteins modulates bacterial detection, specifically targeting Shigella flexneri through evolutionary changes.
bioRxiv · Jul 2, 2019Microbiology