Isoindole-benzohydrazide derivative potentiates colistin activity to overcome resistance conferred by MCR-1 variants in Escherichia coli
A. S. Wolf, Ruth O Ndupu, John N. Alumasa
This study identifies JNAL-042, an isoindole-benzohydrazide derivative that enhances colistin activity against MCR-1-resistant E. coli.
bioRxiv · Oct 12, 2026 · PreprintMicrobiology