Transcriptional activation of cyclin D1 via HER2/HER3 contributes to cell survival and EGFR tyrosine kinase inhibitor resistance in non-small cell lung carcinoma
B. Liu, D. Chen, S. Chen, A. Saber, H. J. Haisma
The paper investigates mechanisms of EGFR-TKI resistance in NSCLC, showing HER2/HER3 activation and cyclin D1 upregulation contribute to cell survival and resistance.
bioRxiv · Nov 21, 2019Cancer Biology