In situ cryo-electron tomography of beta-amyloid and tau in post-mortem Alzheimer's disease brain
M. A. G. Gilbert, N. Fatima, J. Jenkins, T. J. O'Sullivan, A. Schertel, Y. Halfon, T. H. J. Morrema, M. Geibel, S. E. Radford, J. J. M. Hoozemans, R. A. W. Frank
This study uses cryo-electron tomography to examine the in situ structure of beta-amyloid and tau in Alzheimer's disease brain tissue, revealing distinct structural features and spatial organization.
bioRxiv · Jul 17, 2023 · PreprintPathology