J. Jenkins

An ingestible, battery-free, tissue-adhering robotic interface for non-invasive and chronic electrostimulation of the gut

This paper develops an ingestible, battery-free robotic interface for chronic gut electrostimulation, showing it can modulate ghrelin levels and has potential for treating gastrointestinal conditions.

Electroadhesive hydrogel interface for prolonged mucosal theranostics

This paper develops e-GLUE, an electroadhesive hydrogel interface that enables prolonged mucosal retention and demonstrates its utility in GI theranostics.

A Vibrating Ingestible BioElectronic Stimulator Modulates Gastric Stretch Receptors for Illusory Satiety

The paper develops an ingestible device that activates gastric stretch receptors to reduce food intake and weight gain in swine.

In situ cryo-electron tomography of beta-amyloid and tau in post-mortem Alzheimer's disease brain

This study uses cryo-electron tomography to examine the in situ structure of beta-amyloid and tau in Alzheimer's disease brain tissue, revealing distinct structural features and spatial organization.

Seagrass genomes reveal a hexaploid ancestry facilitating adaptation to the marine environment

This study presents chromosome-level genome assemblies of seagrass species and identifies ancient and recent genome duplication events linked to adaptation to marine environments.

Drinkable, liquid in situ-forming and tough hydrogels for gastrointestinal therapeutics

This paper develops LIFT hydrogels that form in the stomach to deliver drugs with controlled release, improving bioavailability and reducing toxicity.

Ocean currents drive the worldwide colonization of the most widespread marine plant, eelgrass (Zostera marina)

The paper reconstructs the colonization history of eelgrass using genomic data, showing trans-Pacific currents drove its spread and Atlantic populations arrived more recently with lower genetic diversity.

The western redcedar genome reveals low genetic diversity in a self-compatible conifer

The paper assembles the western redcedar genome and finds it has low genetic diversity, suggesting mechanisms like associative overdominance maintain genetic variation despite selfing.

Human anti-ACE2 monoclonal antibodies as pan-sarbecovirus prophylactic agents

The paper develops human monoclonal antibodies targeting the ACE2 receptor to block infection by SARS-CoV-2 and related sarbecoviruses, showing broad efficacy against variants and no adverse effects on ACE2 function.

The genome of stress tolerant crop wild relativePaspalum vaginatum leads to increased biomassproductivity in the crop Zea mays

This study sequenced Paspalum vaginatum, a stress-tolerant wild relative of maize, and found that inducing trehalose accumulation in maize increases biomass through autophagy.

Within-Arctic horizontal gene transfer as a driver of convergent evolution in distantly related microalgae

The paper identifies horizontal gene transfer as a driver of convergent evolution in Arctic microalgae, highlighting ice-binding domain gene transfers between distantly related species.

Novel insights into joint estimations of demography, mutation rate, and selection using UV sex chromosomes

This study examines how anisogamy influences genetic variation in moss using UV sex chromosomes, finding sex-biased mutation and selection but no model explaining observed diversity ratios.

The Ceratodon purpureus genome uncovers structurally complex, gene rich sex chromosomes

The paper compares genomes of male and female mosses to study sex chromosome evolution, finding gene-rich, non-degenerated UV sex chromosomes.

The Aquilegia genome: adaptive radiation and an extraordinarily polymorphic chromosome with a unique history

The paper presents the genome of Aquilegia coerulea and shows extensive allele sharing and introgression among species, with a unique chromosome evolutionary history.

The genetic architecture of shoot and root trait divergence between upland and lowland ecotypes of a perennial grass.

The paper investigates the genetic basis of trait divergence between upland and lowland ecotypes of a perennial grass, focusing on adaptation to soil water availability.

Size uniformity of animal cells is actively maintained by a p38 MAPK-dependent regulation of G1-length

The p38 MAPK pathway coordinates cell growth and cell cycle progression by lengthening G1 in small cells, allowing them more time to grow before their next division.

The Sorghum bicolor reference genome: improved assembly and annotations, a transcriptome atlas, and signatures of genome organization

This paper improves the Sorghum bicolor reference genome, annotates it, and constructs a transcriptome atlas, revealing genomic features and gene expression patterns across developmental stages.