Adaptive subsets limit the anti-tumoral NK-cell activity in Hepatocellular Carcinoma
C. Rennert, C. Tauber, P. Fehrenbach, K. Heim, D. Bettinger, O. Sogukpinar, A. Schuch, B. F. Zecher, B. Bengsch, S. Lang, P. Bronsert, N. K. Bjoerkstroem, S. Fichtner-Feigl, M. Schultheiss, R. Thimme, M. Hofmann
This study shows that adaptive NK cells have reduced anti-tumoral activity in HCC patients, particularly in those with HBV infection, and are expanded in such cases.
bioRxiv · Apr 16, 2021Immunology