Author

R. Thimme

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Assay:flow cytometry· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Bengsch· 3 shared M. Hofmann· 3 shared C. Neumann-Haefelin· 2 shared D. Bettinger· 2 shared M. Panning· 2 shared O. Sogukpinar· 2 shared T. Boettler· 2 shared A. Anand· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersImmunology

B. Bengsch

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

KRas, in addition to Tp53 is a driver for early carcinogenesis and a molecular target in a mouse model of invasive gastro-esophageal adenocarcinoma

A. Anand, L. Schoemig, S. Lange, L. Tran, K. Flisikowski, R. Oellinger, R. Rad, M. Vieth, K. Steiger, T. Baumeister, J. Strangmann, H. Alguel, K. Ciecielski, K. Boettcher, H.-Y. Fang, , M. Quante

This study identifies KRAS mutation as a driver of invasive gastro-esophageal adenocarcinoma in a mouse model, showing its synergistic role with Tp53 or Rb1 loss and potential as a therapeutic target.

bioRxiv · May 7, 2024 · PreprintCancer Biology

Efficient formation and maintenance of humoral and CD4 T cell immunity targeting the viral capsid in acute-resolving hepatitis E infection

B. Csernalabics, M. S. Marinescu, L. Maurer, L. Kelsch, J. Werner, K. Baumann, K. Zoldan, M. Panning, P. Reuken, T. Bruns, B. Bengsch, C. Neumann-Haefelin, M. Hofmann, R. Thimme, V. L. Dao Thi, T. Boettler

The paper longitudinally characterizes HEV-specific CD4 T cells and neutralizing antibodies targeting nHEV and eHEV in acute and resolved HEV infection, finding capsid-specific immunity dominates and correlates with nAb responses.

bioRxiv · Oct 19, 2023Immunology

Adaptive subsets limit the anti-tumoral NK-cell activity in Hepatocellular Carcinoma

C. Rennert, C. Tauber, P. Fehrenbach, K. Heim, D. Bettinger, O. Sogukpinar, A. Schuch, B. F. Zecher, B. Bengsch, S. Lang, P. Bronsert, N. K. Bjoerkstroem, S. Fichtner-Feigl, M. Schultheiss, R. Thimme, M. Hofmann

This study shows that adaptive NK cells have reduced anti-tumoral activity in HCC patients, particularly in those with HBV infection, and are expanded in such cases.

bioRxiv · Apr 16, 2021Immunology

Ex vivo detection of SARS-CoV-2-specific CD8+ T cells: rapid induction, prolonged contraction, and formation of functional memory

I. Schulien, J. Kemming, V. Oberhardt, K. Wild, L. M. Seidel, S. Killmer, Sagar, F. Daul, M. Salvat Lago, A. Decker, H. Luxenburger, B. Binder, D. Bettinger, O. Sogukpinar, S. Rieg, , C. Neumann-Haefelin

This study identifies SARS-CoV-2-specific CD8+ T-cell responses, showing their rapid induction, prolonged contraction, and functional memory formation compared to antibody responses.

bioRxiv · Aug 13, 2020 · PreprintImmunology