Author

A. Seetharam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Evolutionary Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

A. Beheshti· 1 shared A. J. Severin· 1 shared B. Aronow· 1 shared C. de Santis Alves· 1 shared D. G. Sashital· 1 shared D. Jackson· 1 shared D. Ware· 1 shared E. Ernst· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperEvolutionary Biology

A. Beheshti

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MaizeCODE reveals bi-directionally expressed enhancers that harbor molecular signatures of maize domestication.

J. Cahn, M. Regulski, J. Lynn, E. Ernst, C. de Santis Alves, S. Ramakrishnan, K. Chougule, S. Wei, Z. Lu, X. Xu, J. Drenkow, M. Kramer, A. Seetharam, M. B. Hufford, W. R. McCombie, , R. A. Martienssen

The paper identifies bi-directionally expressed enhancers in maize with domestication signatures using integrated epigenomic and transcriptomic data from multiple tissues and inbred lines.

bioRxiv · Feb 22, 2024Plant Biology

A pan-tissue, pan-disease compendium of human orphan genes

U. Singh, J. Haltom, J. Guarnieri, J. Li, A. Seetharam, A. Beheshti, B. Aronow, E. S. Wurtele

The paper identifies thousands of human orphan genes from RNA-Seq data, validates them with single-cell RNA-seq, and provides a compendium for future research.

bioRxiv · Feb 21, 2024 · PreprintEvolutionary Biology

Pervasive off-target and double-stranded DNA nicking by CRISPR-Cas12a

K. Murugan, A. Seetharam, A. J. Severin, D. G. Sashital

This study investigates Cas12a cleavage specificity, revealing pervasive off-target nicking and double-stranded DNA degradation, which may impact its use in genome editing.

bioRxiv · Jun 2, 2019 · PreprintBiochemistry