Author

A. Shafer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:behavioral assay· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Alag· 1 shared A. Lakhani· 1 shared C. Kessler· 1 shared D. Nicolaou· 1 shared E. Salvestrini· 1 shared E. Wootton· 1 shared F. M. Grover· 1 shared G. Amico· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperBioengineering

A. Alag

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Humans Exploit the Trade-Off Between Lateral Stability and Manoeuvrability During Walking

R. N. Kulkarni, F. M. Grover, A. Shafer, X. Schmitz, K. E. Gordon

The paper shows people adjust lateral stability during walking based on environment and anticipated movements, supporting a trade-off between stability and manoeuvrability.

bioRxiv · Jun 6, 2023 · PreprintBioengineering

Speciation without gene-flow in hybridising deer

C. Kessler, E. Wootton, A. Shafer

This study examines speciation in hybridising deer species, finding no historical gene flow and instead detecting balancing selection related to immunity and sensory perception.

bioRxiv · Apr 20, 2022Evolutionary Biology

Rational Tuning of CAR Tonic Signaling Yields Superior T-Cell Therapy for Cancer

X. Chen, M. Khericha, A. Lakhani, X. Meng, E. Salvestrini, L. C. Chen, A. Shafer, A. Alag, Y. Ding, D. Nicolaou, J. O. Park, Y. Y. Chen

This study shows that tuning CAR tonic signaling improves T-cell therapy efficacy by designing CARs with low but non-zero tonic signaling, enhancing anti-tumor activity in mouse models.

bioRxiv · Oct 1, 2020 · PreprintBioengineering

The Biogeography of Dromiciops in Southern South America: middle Miocene transgressions, speciation and associations with Nothofagus

J. F. Quintero-Galvis, P. Saenz-Agudelo, G. Amico, S. Vazquez, J. Celis-Diez, A. Shafer, R. Nespolo

This paper reevaluates the biogeographic history of Dromiciops, finding Miocene divergence rather than Pleistocene glaciation, and links diversification to Middle Miocene transgressions and Nothofagus forests.

bioRxiv · Aug 12, 2020Evolutionary Biology