Author

J. O. Park

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Alag· 1 shared A. Lakhani· 1 shared A. Nakano· 1 shared A. Pfeiffer· 1 shared A. Shafer· 1 shared C. A. Perez-Ramirez· 1 shared C. G. King· 1 shared D. Nicolaou· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperBioengineering

A. Alag

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Atlas of fetal metabolism during mid-to-late gestation and diabetic pregnancy

C. A. Perez-Ramirez, H. Nakano, R. C. Law, N. Matulionis, J. Thompson, A. Pfeiffer, J. O. Park, A. Nakano, H. R. Christofk

The paper maps fetal metabolism during mid-to-late gestation in normal and diabetic pregnancies, identifying metabolic changes due to maternal hyperglycemia.

bioRxiv · Mar 16, 2023Cell Biology

Rational Tuning of CAR Tonic Signaling Yields Superior T-Cell Therapy for Cancer

X. Chen, M. Khericha, A. Lakhani, X. Meng, E. Salvestrini, L. C. Chen, A. Shafer, A. Alag, Y. Ding, D. Nicolaou, J. O. Park, Y. Y. Chen

This study shows that tuning CAR tonic signaling improves T-cell therapy efficacy by designing CARs with low but non-zero tonic signaling, enhancing anti-tumor activity in mouse models.

bioRxiv · Oct 1, 2020 · PreprintBioengineering

E. coli translation strategies differ across nutrient conditions

S. H.-J. Li, Z. Li, J. O. Park, C. G. King, J. D. Rabinowitz, N. S. Wingreen, Z. Gitai

This study shows E. coli uses different translation strategies under carbon, nitrogen, and phosphate limitations to maintain protein production rates while adapting to nutrient availability.

bioRxiv · Jan 24, 2018Microbiology