A preclinical model of THC edibles that produces high-dose cannabimimetic responses.
A. English, F. Uittenbogaard, A. Torrens, D. Sarroza, A. Slaven, D. Piomelli, M. Bruchas, N. Stella, B. B. Land
This paper develops a THC edible formulation and access paradigm in mice to study voluntary high-dose THC consumption and its cannabimimetic effects, finding sex-dependent behavioral responses.
bioRxiv · Nov 23, 2022Animal Behavior & Cognition