Author

D. Piomelli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Animal Behavior & Cognition· 1 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:metabolomics· 2

Frequent Co-Authors

A. Torrens· 3 shared F. Assogna· 2 shared F. Palese· 2 shared G. Spalletta· 2 shared N. Realini· 2 shared P. Bossu· 2 shared A. Armirotti· 1 shared A. Basit· 1 shared

Activity by Year

2018-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersPharmacology & Toxicology

A. Torrens

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A preclinical model of THC edibles that produces high-dose cannabimimetic responses.

A. English, F. Uittenbogaard, A. Torrens, D. Sarroza, A. Slaven, D. Piomelli, M. Bruchas, N. Stella, B. B. Land

This paper develops a THC edible formulation and access paradigm in mice to study voluntary high-dose THC consumption and its cannabimimetic effects, finding sex-dependent behavioral responses.

bioRxiv · Nov 23, 2022Animal Behavior & Cognition

ADOLESCENT EXPOSURE TO LOW-DOSE THC DISRUPTS ENERGY BALANCE AND ADIPOSE ORGAN HOMEOSTASIS IN ADULTHOOD

L. Lin, K.-M. Jung, J. Le, G. Colleluori, C. Wood, H.-L. Lee, F. Palese, E. Squire, S. Su, A. Torrens, Y. Fotio, L. Tang, C. Yu, Q. Yang, L. Huang, , D. Piomelli

This study shows that adolescent exposure to low-dose THC leads to metabolic changes in adulthood, including reduced fat mass and adipose dysfunction.

bioRxiv · Jul 26, 2022Pharmacology & Toxicology

Targeting NAAA counters dopamine neuron loss and symptom progression in mouse models of Parkinson's disease

F. Palese, S. Pontis, N. Realini, A. Torrens, F. Ahmed, F. Assogna, C. Pellicano, P. Bossu, G. Spalletta, K. N. Green, D. Piomelli

This study shows that inhibiting NAAA, which deactivates PEA, protects dopamine neurons and reduces Parkinson's symptoms in mouse models.

bioRxiv · Feb 10, 2022 · PreprintPharmacology & Toxicology

N-acylethanolamine acid amide hydrolase is a novel target for drugs against SARS-CoV-2 and Zika virus

M. Lai, V. La Rocca, R. Amato, E. Iacono, c. filipponi, E. Catelli, L. Bogani, R. Fonnesu, g. lottini, A. De Carli, A. Mengozzi, S. Masi, P. Quaranta, P. G. Spezia, G. Freer, , M. Pistello

This paper shows that inhibiting NAAA reduces SARS-CoV-2 and ZIKV replication and inflammation in cell lines and human PBMCs.

bioRxiv · Feb 8, 2022 · PreprintMicrobiology

Elevated plasma ceramide levels in post-menopausal women

V. Vozella, A. Basit, F. Piras, N. Realini, A. Armirotti, P. Bossu, F. Assogna, S. L. Sensi, G. Spalletta, D. Piomelli

This study finds that aging is associated with increased plasma ceramide levels in women, which may be linked to lower estradiol levels in post-menopausal women.

bioRxiv · Jul 9, 2018Biochemistry