An Arginine-Rich Motif in the ORF2 Capsid Protein Regulates the Hepatitis E Virus Lifecycle and Interactions with the Host Cell
K. Hervouet, M. Ferrie, M. Ankavay, C. Montpellier, C. Camuzet, V. Alexandre, A. Dembele, C. Lecoeur, A. T. Foe, P. Bouquet, D. Hot, T. Vausselin, J.-M. Saliou, S. Salome-Desnoulez, L. Marsollier, , L. Cocquerel
This study identifies an Arginine-Rich Motif in the HEV ORF2 capsid protein that regulates its subcellular localization, functionality, and interactions with host cells, revealing its central role in the HEV lifecycle.
bioRxiv · May 26, 2021Microbiology