Author

A. T. S

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2 Organism:rat· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

I. Biswas· 4 shared S. S. Kuduvalli· 4 shared D. P. S· 2 shared D. S. Precilla· 2 shared A. K. B· 1 shared A. Kumar B· 1 shared A. R. Muralidharan· 1 shared A. S· 1 shared

Activity by Year

2022-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersCancer Biology

I. Biswas

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4 papers

Recent·Most cited

The synergistic anti-Warburg efficacy of temozolomide, metformin and epigallocatechin gallate in glioblastoma

S. S. Kuduvalli, D. S. Precilla, I. Biswas, A. T. S

This study evaluates the anti-Warburg efficacy of temozolomide, metformin, and epigallocatechin gallate in glioblastoma models, showing reduced glucose uptake and reversed Warburg effect.

Toxicology and Applied Pharmacology · Dec 1, 2024Peer-reviewedCancer Biology

Dynamics of repurposing synthetic and natural compounds against WNT/β-Catenin signaling in glioma- An in vivo approach

D. P. S, S. S. Kuduvalli, I. Biswas, B. K, A. K. B, J. M. Thomas, A. T. S

This study evaluates a quadruple-drug combination targeting WNT/β-catenin signaling in glioma using an in vivo xenograft model, showing reduced proliferation and increased apoptosis.

bioRxiv · Dec 2, 2022 · PreprintCancer Biology

Unveiling the anti-glioma potential of a marine derivative, Fucoidan: its synergistic cytotoxicity with Temozolomide-an in vitro and in silico experimental study

I. Biswas, D. S. Precilla, S. S. Kuduvalli, M. A. Ramachandran, A. S, V. Raman, D. Prabhu, A. T. S

This study evaluates the synergistic anti-glioma effects of Fucoidan with Temozolomide in vitro and in silico, showing reduced cell viability, migration, and inflammation with increased apoptosis.

bioRxiv · Dec 2, 2022 · PreprintCancer Biology

A combination of Metformin and Epigallocatechin Gallate Potentiates Glioma Chemotherapy in vivo

S. S. Kuduvalli, D. P. S, A. Vaithy, M. Purushothaman, A. R. Muralidharan, A. Kumar B, M. Mezger, J. S. Antony, M. Subramani, B. Dubashi, I. Biswas, G. K P, A. T. S

This study shows that combining metformin, epigallocatechin gallate, and temozolomide improves glioma treatment in rats by inhibiting tumor growth and increasing survival.

bioRxiv · Nov 16, 2022 · PreprintCancer Biology