New Soluble Angiopoietin Analog of C4BP-ANG1 Prevents Pathological Vascular Leakage
P. Liu, M. Ryczko, X. Xie, A. Taiyab, H. Sheardown, S. E. Quaggin, J. Jin
The paper designs a soluble ANGPT1 mimetic, C4BP-ANG1, which activates Tie2 and reduces vascular leakage in models of inflammation.
bioRxiv · Mar 30, 2020Biochemistry