Ultrasound- and microbubble-mediated targeted delivery of therapeutic microRNA-loaded nanocarriers to deep liver and kidney tissues in pigs
T. di Ianni, R. J. C. Bose, U. K. Sukumar, S. Bachawal, H. Wang, A. Telichko, C. D. Herickhoff, E. Robinson, S. Baker, J. G. Vilches-Moure, S. A. Felt, S. S. Gambhir, R. Paulmurugan, J. D. Dahl
This study validates a platform for ultrasound and microbubble-mediated delivery of microRNA-loaded nanocarriers to deep liver and kidney tissues in pigs, showing enhanced delivery and no tissue damage.
bioRxiv · Jun 3, 2019Bioengineering