The monosialoganglioside GM1a protects trophoblasts, erythrocytes and endothelial cells against complement attack
H. Wedekind, J. Beimdiek, C. Rossdam, E. Kats, V. Wittek, L. Schumann, A. Tiede, F. F. R. Buettner, B. Weinhold, A. Muenster-Kuehnel, M. Abeln
This study identifies GM1a as a complement regulator that protects trophoblasts, erythrocytes, and endothelial cells from complement attack through factor H recruitment.
bioRxiv · Jan 24, 2022Biochemistry