Author

A. Trovato

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 3 Approach:statistical model· 3 Assay:protein structure· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:protein sequence· 1

Frequent Co-Authors

A. Ghafoor· 1 shared A. Ghodousi· 1 shared A. H. Rizvi· 1 shared A. Lazzari· 1 shared A. Maritan· 1 shared A. Q. Baloch· 1 shared D. M. Cirillo· 1 shared E. Borroni· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperMicrobiology

A. Ghafoor

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Author profile →

5 papers

Recent·Most cited

Folding kinetics of an entangled protein

L. Salicari, M. Baiesi, E. Orlandini, A. Trovato

This paper studies the folding kinetics of an entangled protein, finding that entanglement leads to distinct kinetic intermediates and folding pathways.

bioRxiv · Apr 17, 2023Biophysics

A scale-invariant log-normal droplet size distribution below the critical concentration for protein phase separation

T. Amico, S. Dada, A. Lazzari, M. Brezinova, A. Trovato, M. Vendruscolo, M. Fuxreiter, A. Maritan

The paper investigates droplet size distributions in protein phase separation and finds they follow a scale-invariant log-normal function, suggesting universal behavior and a method to estimate critical concentration.

bioRxiv · Apr 11, 2023Biophysics

Sequence based prediction of protein phase separation into disordered condensates using machine learning

P. Mullick, A. Trovato

This paper develops a machine learning model to predict whether a protein undergoes liquid-liquid phase separation based on its amino-acid sequence.

bioRxiv · Dec 13, 2021 · PreprintBiophysics

Statistical potentials from the Gaussian scaling behaviour of chain fragments buried within protein globules

S. Zamuner, F. Seno, A. Trovato

The paper derives sequence-independent and sequence-dependent interaction potentials for proteins by analyzing Gaussian statistics of buried chain fragments in globular structures.

bioRxiv · Aug 4, 2021Biophysics

Acquisition of cross-resistance to bedaquiline and clofazimine following treatment for tuberculosis in Pakistan

A. Ghodousi, A. H. Rizvi, A. Q. Baloch, A. Ghafoor, F. M. Khanzada, M. Qadir, E. Borroni, A. Trovato, S. Tahseen, D. M. Cirillo

The paper reports six cases of acquired resistance to bedaquiline and clofazimine in Pakistan, documenting mutations and MIC increases in tuberculosis patients on bedaquiline-containing regimens.

bioRxiv · May 7, 2019Microbiology