Inhibition of pyruvate dehydrogenase affects the brain protein acylation stronger than PDHA phosphorylation at Ser293
V. A. Aleshin, D. A. Sibiryakina, A. V. Kazantsev, A. V. Graf, V. I. Bunik
The paper investigates how inhibition of pyruvate dehydrogenase affects brain protein acylation, showing differential impacts on acetylation and succinylation based on inhibitor type and protein size.
bioRxiv · Nov 10, 2022Biochemistry