Author

V. A. Aleshin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

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Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

V. I. Bunik· 2 shared A. V. Graf· 1 shared A. V. Kazantsev· 1 shared D. A. Sibiryakina· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersBiochemistry

V. I. Bunik

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2 papers

Recent·Most cited

Protein-protein interfaces as druggable targets: A common motif of the pyridoxal-5'-phosphate-dependent enzymes to receive the coenzyme from its producers

V. A. Aleshin, V. I. Bunik

The paper identifies a common motif in PLP-dependent enzymes that may facilitate direct PLP transfer from donors to acceptors, with implications for drug development targeting malignant cells.

bioRxiv · Feb 13, 2023Biochemistry

Inhibition of pyruvate dehydrogenase affects the brain protein acylation stronger than PDHA phosphorylation at Ser293

V. A. Aleshin, D. A. Sibiryakina, A. V. Kazantsev, A. V. Graf, V. I. Bunik

The paper investigates how inhibition of pyruvate dehydrogenase affects brain protein acylation, showing differential impacts on acetylation and succinylation based on inhibitor type and protein size.

bioRxiv · Nov 10, 2022Biochemistry