The C-terminal non-catalytic domain of Mkp-1 phosphatase harbors a complex signal for rapid proteasome degradation in enterocytes
J. Wang, A. V. Grishin, P. Delaplain, C. P. Gayer, H. R. Ford
This study identifies the C-terminal non-catalytic domain of Mkp-1 as containing multiple elements that mediate its rapid proteasome-dependent degradation in enterocytes, independent of ERK phosphorylation.
bioRxiv · Jun 21, 2019 · PreprintImmunology