pHluo_M153R-CD63, a bright, versatile live cell reporter of exosome secretion and uptake, reveals pathfinding behavior of migrating cells
B. H. Sung, A. von Lersner, J. Guerrero, D. Inman, R. J. Pelletier, A. Zijlstra, S. M. Ponik, A. M. Weaver
The paper introduces an improved exosome reporter, pHluorin-CD63 with M153R mutation, enabling stable visualization of exosome secretion and uptake in live cells and reveals their role in cell migration.
bioRxiv · Jun 26, 2019Cell Biology